Vitis Vinifera

Vitis vinifera (grape-derived) ingredients are typically used as extracts/oils for antioxidant/emollient benefits, but plant-derived extracts contain complex polyphenols and other constituents that can trigger stinging or contact dermatitis in reactive or eczematous skin. While generally well-tolerated at common cosmetic concentrations, the variability in extract composition and documented cases of botanical sensitization justify a mild irritancy score with caution for highly sensitive users. Safety Notes: In commercial skincare, Vitis vinifera–derived materials (most commonly grape seed extract, grape fruit extract, grape water/juice, or grape seed oil) are frequently used at very low levels (around 0.0001–0.1%) as label-claim botanicals in both leave-on and rinse-off products. Mid-range use (0.5–3%) is common when the ingredient is intended to contribute measurable antioxidant/emollient performance, particularly in serums, creams, and masks. High-strength consumer-available products such as grape seed oil–focused face oils and some botanical-heavy creams can use about 5–10% of a grape-derived component (especially the oil), while higher levels are uncommon due to sensorial, stability/oxidation, and cost constraints; there is no specific EU/FDA maximum for grape-derived cosmetic ingredients beyond general safety requirements.