Vaccinium Macrocarpon Fruit Extract

Vaccinium Macrocarpon (cranberry) fruit extract is typically used at low concentrations as an antioxidant/soothing “botanical” additive, but it contains organic acids and polyphenols that can sting or trigger irritant reactions in compromised barriers. Clinical experience and patch testing trends with botanical extracts show a small but real rate of irritation/sensitization in reactive or eczematous skin, especially when layered with other actives; therefore it is best classified as mildly irritating rather than inherently gentle. Safety Notes: In mass-market leave-on skincare (serums/lotions/eye creams) Vaccinium Macrocarpon (Cranberry) Fruit Extract is frequently used as a supporting antioxidant/marketing extract at very low levels (often ~0.001–0.1%), consistent with typical supplier-recommended use levels for botanical extracts. Higher-strength consumer-available products—especially “superfood/antioxidant” masks, treatment serums, and some rinse-off cleansers—can reach ~1–5% when the extract is a primary featured botanical, with upper use constrained by odor/color, stability, and cost rather than specific regulatory limits.