Tricaprylin

Tricaprylin is a medium-chain triglyceride emollient/solvent used at relatively high levels in skincare to improve slip and reduce transepidermal water loss; it is generally well-tolerated and commonly used in sensitive-skin formulas. Clinical and patch-test experience shows a low rate of irritation/sensitization compared with surfactants, acids, or fragrances, though rare irritant or follicular intolerance can occur in highly reactive patients or with occlusive layering. Given its broad compatibility but non-zero risk in compromised barriers, it best fits a very gentle score rather than completely inert. Safety Notes: In commercial skincare, tricaprylin is frequently used at low levels (~0.1–2%) as a slip/emollient and solvent for oil-soluble actives in leave-on serums, lotions, sunscreens, and makeup; rinse-off products also use it in this low single-digit range as part of the emollient phase. At the high end, it appears as a primary/major carrier oil in anhydrous facial oils, cleansing oils/balms, and oil-based active concentrates, reaching ~50–90% and, in some consumer-available single-ingredient oil products, up to 100%. There is no specific EU/FDA maximum concentration restriction for tricaprylin itself in cosmetics, so practical use is governed mainly by sensorial goals, solubilization needs, and product format.