Sodium Laurylglucosides Hydroxypropylsulfonate

Sodium Laurylglucosides Hydroxypropylsulfonate is a mild anionic surfactant/cleansing agent typically used in rinse-off cleansers and shampoos (often a few percent active), generally less irritating than SLS but still capable of disrupting the stratum corneum barrier with repeated exposure. Patch-test and real-world use patterns show surfactants remain a common trigger for stinging, dryness, and eczema flares in highly reactive or compromised skin, especially with frequent washing or when combined with other detergents. For patient safety in severe sensitivity/eczema populations, I rate it as mild—usually tolerated, but not “exceptionally gentle” and not risk-free. Safety Notes: In commercial products, this mild anionic surfactant is most often used in rinse-off cleansers where total surfactant actives can vary widely; it appears at very low levels (~0.2–1%) as a secondary co-surfactant/foam booster in gentle facial cleansers and micellar/low-foam washes. At the high end, consumer-available high-foaming body washes, shampoos, and clarifying cleansers can use it as a primary surfactant system component, reaching roughly 10–20% active matter in concentrated or sulfate-free/high-foam formats. It is uncommon in true leave-on products beyond trace/low levels due to irritation potential and sensorial constraints, so the upper end is primarily observed in rinse-off formulations.