Sodium acetylated hyaluronate

Sodium acetylated hyaluronate is a modified hyaluronic acid humectant used at low concentrations (typically well under 1%) to improve hydration and barrier feel; hyaluronate polymers are generally well-tolerated in clinical use and patch testing with very low irritancy rates. Rare stinging or transient redness can occur in highly reactive or severely compromised skin (often influenced by the full formula/pH rather than the polymer itself), so it is not scored as completely inert but remains very gentle for most sensitive users. Safety Notes: In commercial products, sodium acetylated hyaluronate is often used as a premium hyaluronic-acid derivative at very low levels (around 0.0005–0.01%) in multi-HA complexes, emulsions, and toners/cleansers where it functions mainly as a film-forming humectant and label claim ingredient. Leave-on serums and masks marketed for long-lasting hydration commonly sit around 0.01–0.1%, while a small number of high-strength consumer-available “concentrated” HA serums/gels and sheet mask essences push this specific derivative up to ~0.2–0.3% for enhanced substantivity; higher levels are uncommon due to cost, viscosity/tack, and formulation aesthetics rather than regulatory limits.