Scutellaria Galericulata Extract

Scutellaria galericulata (skullcap) extract is a botanical antioxidant/soothing agent typically used at low concentrations (often <1–2%) and is generally well-tolerated in leave-on products. However, like many plant extracts, it contains multiple bioactive compounds that can trigger irritant or allergy-type reactions in a minority of highly reactive or eczematous patients, especially with compromised barrier skin. Given this non-zero sensitization potential but overall low clinical irritancy at typical use levels, it fits best as a gentle (not exceptionally gentle) ingredient. Safety Notes: In commercial skincare, Scutellaria Galericulata Extract is most often used as a minor botanical antioxidant/soothing component in complex blends, where it commonly appears around 0.001–0.1% (especially in mass-market leave-on lotions/serums and rinse-off cleansers). Higher-strength consumer products marketed around “skullcap extract” actives or botanical concentrate serums/masks can reach ~1–5% when the extract is a standardized, solvent-based or dry extract equivalent; levels above this are uncommon due to solubility, color/odor impact, and rising irritation/sensitization risk. There is no specific FDA/EU maximum limit for this plant extract, so the upper end is primarily constrained by supplier guidance and formulation aesthetics/stability, with leave-on products typically formulated lower than rinse-off at comparable claims.