Prunus Domestica Seed Extract

Prunus domestica (plum) seed extract is typically used at low concentrations as a botanical antioxidant/skin-conditioning agent, but seed-derived extracts can contain trace aromatic compounds and processing residues that increase reactivity compared with inert emollients. While broad clinical irritation data are limited, botanicals are a common source of unpredictable stinging or dermatitis in eczema-prone patients, especially in leave-on formulas and when layered with other actives. Given the uncertainty and the higher risk profile of plant extracts in compromised skin, a mild irritancy score is the safest clinically-aligned assessment. Safety Notes: In commercial skincare, Prunus domestica (plum) seed extract is most often used as a low-level antioxidant/conditioning botanical in leave-on creams, serums, and eye products, commonly appearing in the 0.001–0.1% range when supplied as a diluted extract in a carrier. Higher-strength consumer products (typically facial oils, balms, and “plum” repair serums) may use concentrated oil/extract blends or “active botanical” phases that bring the effective seed-extract input up to ~1–5% without entering professional-only territory. No specific EU/FDA maximum applies to this extract; practical upper limits are driven by sensory/oxidative stability and supplier-recommended use levels.