Polyglyceryl-2 Dipolyhydroxystearate

Polyglyceryl-2 Dipolyhydroxystearate is a non-ionic emulsifier/structuring agent typically used at low single-digit percentages in creams and makeup, and it is generally well-tolerated because it is not pH-active and does not act as a solvent or exfoliant. Available safety assessments and practical patch-test experience suggest a low rate of irritation compared with harsher surfactants, though any emulsifier can rarely sting or provoke irritation in severely barrier-impaired skin. Given its function and typical exposure level, I rate it as very gentle with minimal but non-zero irritation potential in highly reactive patients. Safety Notes: Polyglyceryl-2 Dipolyhydroxystearate is primarily used as a W/O emulsifier and dispersant in anhydrous-to-low-water systems (water-in-oil foundations, tinted sunscreens, concealers, balm textures), and is observed in commercial formulas at low levels (~0.2–1%) when used mainly as a pigment wetting/dispersing aid or co-emulsifier. In high-structure W/O emulsions and long-wear color cosmetics available OTC, usage commonly rises to ~2–8%, and can reach ~10–15% in specialty high-pigment, high-silicone/anhydrous or very low-water systems where it functions as a primary emulsifier/structurant. Rinse-off products typically sit at the low end (if used at all), while leave-on complexion and sun products drive the upper end of the market range.