Pleiogynium Timoriense Fruit Extract

Pleiogynium timoriense (a botanical fruit extract) is typically used at low concentrations as an antioxidant/conditioning agent, but like many fruit extracts it can contain variable phenolics/organic acids that increase sting risk on compromised or eczematous skin. There is limited standardized human patch-test/HRIPT data specific to this extract, so patient-safety practice is to score it as mild rather than assume inertness, especially in leave-on formulas and when combined with other actives. Safety Notes: Pleiogynium timoriense fruit extract is a niche botanical typically supplied as a diluted glycerin/propylene glycol or butylene glycol extract and is most often used as a label-claim antioxidant/soothing component in leave-on serums/creams at trace-to-low levels (~0.0005–0.1%). Higher consumer-available “botanical concentrate” leave-on products and ampoules can push specialty fruit extracts into the ~1–3% range when the supplier extract is not highly standardized, while rinse-off products generally sit at the lower end due to limited contact time and cost/benefit.