PEG-75

PEG-75 is a low–molecular weight polyethylene glycol used mainly as a humectant/solvent and viscosity modifier, typically at low to moderate percentages in leave-on and rinse-off products. Clinical experience and patch-test data generally show PEGs to be well tolerated with a low rate of irritation or sensitization, though stinging/irritation can occur on compromised skin (e.g., eczema, fissures) or when used alongside other irritants. Given its broad use in sensitive-skin formulations but nonzero risk in barrier-impaired patients, it fits best as very gentle rather than inert. Safety Notes: PEG-75 (a low-molecular-weight polyethylene glycol) is most often used as a humectant/solubilizer and processing aid, showing up at very low levels (~0.05–0.5%) in leave-on lotions/serums and color cosmetics to aid solubilization, slip, and freeze-thaw stability. In rinse-off cleansers/body washes and some hydrating gels or bases, it can be used much higher (commonly 1–5%), with the upper end (~10–15%) seen in consumer-available, high-PEG humectant concentrates and specialty “mix-in” bases where PEGs form a major part of the solvent/humectant system. This range reflects observed OTC market use; PEG-75 is not subject to a specific EU maximum concentration limit, so practical sensorial and compatibility constraints typically set the upper bound.