Myristamidopropyl Pg-Dimonium Chloride Phosphate

Myristamidopropyl PG-dimonium chloride phosphate is a cationic conditioning/surfactant-type ingredient used in haircare and some cleansers/leave-on conditioners at low percentages; cationic quats can be more reactive on compromised or eczematous skin due to their strong surface-binding and barrier-disruptive potential. While generally tolerated in rinse-off formulas, patch-test data across similar quaternary ammonium conditioning agents shows occasional irritant responses (and rare sensitization), so for highly sensitive populations I rate it as mild rather than gentle. Safety Notes: Myristamidopropyl PG-Dimonium Chloride Phosphate is a cationic conditioning/antistatic agent most commonly used in hair conditioners, 2-in-1 shampoos, and cleansing conditioners, with commercial use frequently starting around ~0.1–0.3% active and occasional low-level inclusion down to ~0.05% for light combability/feel benefits. In consumer-available high-conditioning rinse-off products (masks, intensive conditioners, co-washes) and some leave-on detanglers/creams, it is seen at multi-percent levels, with practical OTC upper-end use around ~5% where charge density/viscosity, potential buildup, and irritation constraints typically limit further increases.