Lysolecithin

Lysolecithin is a phospholipid-derived emulsifier and skin-conditioning agent typically used at low concentrations (about 0.1–2%) to support barrier-friendly formulations. Human patch-testing and clinical use suggest a low irritation profile for most users, but because it is a surfactant-like lipid that can increase penetration and occasionally sting on compromised/eczema-prone skin, it is not truly inert. Scoring it as very gentle (0.2) accounts for rare reactivity while remaining consistent with its generally good tolerability. Safety Notes: In commercial skincare, lysolecithin is most often used as a phospholipid co-emulsifier/solubilizer or liposome-supporting component at low levels (~0.05–0.5%) in leave-on lotions, serums, and toners, where it mainly aids dispersion and barrier feel rather than acting as a primary active. Higher consumer-available uses occur in phospholipid-rich barrier creams, cleansing balms/oils, and “liposomal/lamellar” systems where lysolecithin can be pushed into the ~1–5% range to build structure and improve stability/sensory, with higher levels limited by odor/color, tackiness, and potential irritation in leave-on products. No specific FDA/EU cosmetic maximum applies for lysolecithin; practical formulation constraints generally set the upper end in OTC products.