Glycine Max Polypeptide

Glycine Max Polypeptide is a soy-derived peptide/protein skin-conditioning ingredient typically used at low concentrations, and peptides themselves are generally well-tolerated with low intrinsic irritancy. However, soy-derived protein fractions can trigger irritation or allergic reactions in a small subset of highly reactive or atopic patients (protein contact dermatitis/sensitization risk), so it cannot be scored as “very gentle” for compromised skin. Given the low typical use levels but non-zero allergy potential, a conservative ‘gentle’ score is appropriate. Safety Notes: In commercial skincare, Glycine Max (Soybean) Polypeptide is most often used as a low-dose bioactive/conditioning peptide within multi-ingredient complexes, with effective-label usage commonly falling in the ppm-to-0.1% range for leave-on serums/creams and often even lower in rinse-off cleansers. Higher-strength consumer products (typically leave-on “peptide” serums/ampoules and some sheet-mask essences) can reach ~1–5% when the ingredient is supplied as a standardized polypeptide powder or a highly concentrated active solution and positioned as a primary claim ingredient; above this is uncommon due to cost, sensorial/stability limits, and diminishing returns. No specific FDA/EU maximum applies to this INCI beyond general cosmetic safety requirements, so the observed market ceiling is mainly formulation-practical rather than regulatory.