Glyceryl Caprylate

Moderate irritancy

Glyceryl caprylate is a fatty acid monoester used mainly as an emollient/co-emulsifier and as a preservative booster, typically around ~0.2–1%. While generally well tolerated, its antimicrobial/surfactant-like behavior can disrupt barrier lipids and provoke stinging or irritation in compromised skin (e.g., eczema) and has occasional positive patch-test reactions, so I rate it as mild rather than “gentle” for highly reactive patients. Safety Notes: In commercial skincare, glyceryl caprylate is commonly used at very low levels (~0.05–0.3%) as a co-emulsifier/emollient and as a preservative booster (often in leave-on creams/lotions and some rinse-off cleansers). Many industry formulating guidelines place it around ~0.1–1% depending on the emulsifier system and preservation strategy, and this aligns with typical INCI-declared products. Higher-strength consumer products (e.g., minimalist anhydrous/oil-based blends, deodorant-style or antimicrobial-support formulations, and some concentrated emulsifier systems) can reach ~3–5%, which represents the upper end seen in OTC products before sensorial/irritancy and formula-structure constraints become limiting.

Identifiers

CAS
26402-26-6
CosIng
34049