Dipotassium Glycyrrhizate

Dipotassium glycyrrhizate (a licorice-derived salt) is primarily used as a soothing/anti-inflammatory agent, typically around ~0.1–1% in leave-on products, and is generally well-tolerated in patch testing and sensitive-skin use. True irritation or allergy appears uncommon, but as a botanical-derived active there is still a small, real risk of reactivity in highly eczema-prone patients, so it is not scored as fully inert. Safety Notes: In commercial skincare, dipotassium glycyrrhizate is commonly used as a soothing/anti-redness and skin-comfort agent, with low-end usage around 0.01–0.05% in mass-market cleansers, toners, and emulsions where it is a minor supportive additive. Typical leave-on formulas (serums, creams, sunscreens) more often sit around ~0.1–0.5% based on industry practice and product disclosures aligned with published anti-inflammatory/brightening use levels. High-strength consumer OTC formulations—especially targeted calming/spot-repair serums and some Asian-market quasi-drug style products—can reach about 1–2%, above which solubility, tack/feel, and diminishing returns tend to limit further increases; this ingredient appears in both leave-on and rinse-off products, but the upper end is predominantly leave-on.