Cucurbita Pepo Seed Extract

Cucurbita pepo (pumpkin) seed extract is primarily used as a soothing/conditioning antioxidant extract, typically included at low concentrations (about 0.1–2%) in leave-on products, and it is not a pH-dependent active. Clinical experience and patch-testing trends suggest a low baseline irritancy, though botanical extracts can occasionally trigger irritation or allergic contact dermatitis in highly reactive or eczema-prone patients due to natural protein/trace component variability. Given sensitive-skin safety priorities, it fits a very gentle profile but not truly inert. Safety Notes: In mass-market leave-on skincare (creams/serums/eye products) and shampoos/cleansers, Cucurbita Pepo (pumpkin) seed extract is commonly used as a minor botanical active or claim ingredient at ~0.01–0.5%, with the low end reflecting formulas using it primarily for marketing or as part of a botanical blend. Higher-strength OTC “hair-thinning/scalp” and anti-androgen/sebum-control style products, as well as some natural/deodorant and men’s grooming leave-ons, can push dedicated extract usage into the ~1–5% range depending on extract form and carrier; above this is uncommon due to cost, solubility/odor, and sensory constraints. Rinse-off products typically sit toward the lower-middle of the range, while concentrated leave-on scalp treatments and targeted serums represent the upper end.