Cucumis Sativus Seed Extract

Cucumis Sativus (cucumber) seed extract is typically used at low concentrations as a soothing/antioxidant botanical and is generally well-tolerated in leave-on products. However, as a plant extract it contains multiple bioactive components that can trigger irritation or allergy in a small subset of highly reactive or eczema-prone patients, especially on compromised skin. Given this non-zero but low, formulation-dependent risk, it fits best as a "Gentle" ingredient rather than "Very gentle" or "Inert." Safety Notes: In commercial skincare, Cucumis Sativus (cucumber) seed extract is most often used as a low-level soothing/antioxidant botanical at trace-to-labeling levels (~0.001–0.1%) in leave-on toners, serums, and creams, and similarly low in rinse-off cleansers due to short contact time. Higher-strength consumer products (e.g., “botanical-forward” gels/serums or formulas built around a glycerin/butylene glycol extract solution) can reach ~1–5% of the finished formula when the supplier extract is used as a primary supporting active. Levels above ~5% are uncommon in OTC products because many commercial extracts are supplied in solvent carriers and become limited by stability, odor/color, and overall formula balance rather than regulatory caps.