Cellulose

Cellulose is a plant-derived polysaccharide used primarily as a thickening agent, film-former, and absorbent in concentrations typically ranging from 0.1-5%. Clinical patch testing data consistently shows cellulose to be non-irritating and non-sensitizing, with exceptional tolerability even in compromised skin populations including post-procedure and atopic dermatitis patients. Its large molecular structure prevents penetration, and it functions as an inert structural component with no known biochemical activity that could trigger inflammation or immune responses. Safety Notes: Cellulose and its derivatives (microcrystalline cellulose, cellulose gum) appear in commercial skincare products across a wide concentration spectrum. At the low end (0.1-1%), cellulose functions as a minor thickener or texture modifier in serums and lightweight lotions. At the high end (10-15%), it serves as a primary rheology modifier and film-former in specialized products like peel-off masks, mattifying primers, and oil-absorbing formulations where substantial structure and absorbency are required. Both leave-on and rinse-off products utilize the full range depending on the desired texture and performance characteristics.