Capryloyl Glycerin/Sebacic Acid Copolymer

Capryloyl Glycerin/Sebacic Acid Copolymer is a high–molecular weight film-forming/emollient polymer used at low levels (typically ~0.5–5%) to improve texture, reduce transepidermal water loss, and enhance wear. As a non-volatile, non-acidic polymer in finished products, it has low penetration and is not commonly associated with positive patch-test reactions; irritation is generally limited to rare cases of stinging on severely compromised skin or when combined with multiple actives. Given its favorable tolerability profile but acknowledging that even inert-leaning film formers can occasionally bother highly reactive eczema skin, it fits best as "very gentle" rather than completely inert. Safety Notes: In commercial skincare, Capryloyl Glycerin/Sebacic Acid Copolymer is typically used as an emollient/film-forming sensory modifier and appears at low levels (~0.1–1%) in moisturizers, sunscreens, and primers where it supports slip and a soft-focus/velvety afterfeel. It is also sold within consumer-available “silicone-alternative” or texture-enhancing systems and anhydrous/low-water balms where total polymer levels can reach mid-to-high single digits; the upper end observed in OTC leave-on products is around ~10% when the polymer is a primary structurant/film former. Rinse-off products generally sit toward the low end due to cost and limited deposition benefit compared with leave-on formats.