Aspergillus Ferment

Aspergillus Ferment is typically used at low concentrations as a skin-conditioning/enzymatic ferment filtrate and is generally well-tolerated in clinical use, with low rates of irritation in most users. However, because it is a biologically derived mixture that can contain residual proteins/enzymatic components, it carries a small but real risk of irritation or sensitization in highly reactive or eczema-prone skin, especially when paired with other actives. For patient safety in severe sensitivities, I score it as gentle rather than very gentle. Safety Notes: In commercial skincare, Aspergillus Ferment is most commonly supplied as a diluted ferment filtrate or enzyme-active blend and is often used at very low levels (~0.01–0.1%) in leave-on serums/essences and moisturizers for mild skin-conditioning or exfoliation support. Mainstream exfoliating masks and enzyme cleansers typically fall around ~0.1–2%, while the highest OTC “enzyme peel/powder” style products and concentrated ferment/enzymatic booster formulas marketed to consumers can reach ~5–10% (often depending on supplier standardization and whether the INCI reflects a concentrate vs a pre-diluted filtrate). Rinse-off products may use higher percentages than leave-on to manage irritation potential and activity control, but both formats exist across the range.