Angelica Polymorpha Sinensis Root Extract

Angelica polymorpha sinensis root extract is a botanical antioxidant/soothing extract typically used at low concentrations, but it contains multiple naturally occurring aromatic compounds (e.g., phthalides/coumarin-like constituents) that can act as irritants in reactive or barrier-impaired skin. While broad human irritation data are limited compared with standard actives, plant extracts show non-trivial rates of stinging/erythema in sensitive populations and can contribute to cumulative irritation in multi-step routines. Given the uncertainty and the higher risk profile in eczema-prone patients, I score it as mild rather than gentle. Safety Notes: In commercial skincare, Angelica Polymorpha Sinensis Root Extract (dong quai/Angelica sinensis) most often appears as a minor botanical in multi-extract blends, where finished-product use levels can be as low as ~0.0001–0.01% (especially when the supplier blend is added at 0.1–1% and the target extract is a small fraction). Leave-on toners/serums/creams commonly use it around 0.05–1% as a named botanical active, while the highest consumer-available “high botanical” or traditional-herbal positioning products (including masks/ampoules) can reach ~2–5% when the formula is built around the extract; rinse-off products generally sit toward the lower end due to cost/benefit and wash-off dilution.